
Climate Change and Emerging Infectious Diseases: A Global Review of Shifting Patterns, Pathogens, and Public Health Risk
Epidemiology and Health Data Insights, 1(3), 2025, ehdi009, https://doi.org/10.63946/ehdi/16744
Publication date: Aug 12, 2025
ABSTRACT
Climate change is changing how emerging infectious diseases (EIDs) spread over the world. The ecological conditions in which diseases, vectors, and hosts interact are changing because of rising temperatures, shifting patterns of rainfall, and increasingly frequent extreme weather events. This narrative review compiles existing research on climate-sensitive infectious illnesses and elucidates the principal mechanisms influencing observed changes. Food- and water-borne illnesses (e.g., cholera, leptospirosis) are increasingly linked to droughts, floods, and disruptions in infrastructure. Vector-borne diseases like dengue, chikungunya, malaria, and Lyme disease are spreading to highland and temperate areas. At the same time, zoonotic spillovers like Ebola, Nipah, and SARS-CoV-2 are happening more commonly in areas where the ecosystem has been altered. New worries are thermotolerant fungal infections and microorganisms that live in permafrost. This review does not offer new epidemiological modelling; instead, it puts recent Global Burden of Disease (GBD) estimates into context. These estimates reveal that the burden of infectious diseases is rising in regions that are sensitive to climate change, including sub-Saharan Africa, South Asia, and Latin America. Weak surveillance systems, health disparities caused by climate change, and broken data streams are some of the biggest gaps in response. Improvements in AI-based forecasting, satellite surveillance, pathogen genomes, and One Health methods provide useful tools for taking action before something happens. It is important to build public health systems that are climate-responsive, transdisciplinary, and fair in order to reduce the growing dangers posed by infectious illnesses connected to climate change.
KEYWORDS
Climate Change Emerging Infectious Diseases Vector-Borne Transmission Zoonotic Spillover One Health Framework
CITATION (Vancouver)
Wright AKA, Ezugwu CI, Iregbu JK, Chisom EP, Ozigbo AA, Ajobiewe MA, et al. Climate Change and Emerging Infectious Diseases: A Global Review of Shifting Patterns, Pathogens, and Public Health Risk. Epidemiology and Health Data Insights. 2025;1(3):ehdi009. https://doi.org/10.63946/ehdi/16744
APA
Wright, A. K.-A., Ezugwu, C. I., Iregbu, J. K., Chisom, E. P., Ozigbo, A. A., Ajobiewe, M. A., Oyekanmi, E. O., & Olaniyi, A. O. (2025). Climate Change and Emerging Infectious Diseases: A Global Review of Shifting Patterns, Pathogens, and Public Health Risk. Epidemiology and Health Data Insights, 1(3), ehdi009. https://doi.org/10.63946/ehdi/16744
Harvard
Wright, A. K.-A., Ezugwu, C. I., Iregbu, J. K., Chisom, E. P., Ozigbo, A. A., Ajobiewe, M. A., . . . Olaniyi, A. O. (2025). Climate Change and Emerging Infectious Diseases: A Global Review of Shifting Patterns, Pathogens, and Public Health Risk. Epidemiology and Health Data Insights, 1(3), ehdi009. https://doi.org/10.63946/ehdi/16744
AMA
Wright AKA, Ezugwu CI, Iregbu JK, et al. Climate Change and Emerging Infectious Diseases: A Global Review of Shifting Patterns, Pathogens, and Public Health Risk. Epidemiology and Health Data Insights. 2025;1(3), ehdi009. https://doi.org/10.63946/ehdi/16744
Chicago
Wright, Alliah Kris-Ann, Cyril Ifeanyichukwu Ezugwu, John Kelenna Iregbu, Ezeamii Patra Chisom, Adaobi Amelia Ozigbo, Morayo Anne Ajobiewe, Ebenezer Oluwadamilare Oyekanmi, and Aliyu Olanrewaju Olaniyi. "Climate Change and Emerging Infectious Diseases: A Global Review of Shifting Patterns, Pathogens, and Public Health Risk". Epidemiology and Health Data Insights 2025 1 no. 3 (2025): ehdi009. https://doi.org/10.63946/ehdi/16744
MLA
Wright, Alliah Kris-Ann et al. "Climate Change and Emerging Infectious Diseases: A Global Review of Shifting Patterns, Pathogens, and Public Health Risk". Epidemiology and Health Data Insights, vol. 1, no. 3, 2025, ehdi009. https://doi.org/10.63946/ehdi/16744
REFERENCES
- World Health Organization. Climate change [Internet]. [cited 2025 Jul 16]. Available from: https://www.who.int/news-room/fact-sheets/detail/climate-change-and-health
- Nunes LJR. The Rising Threat of Atmospheric CO2: A Review on the Causes, Impacts, and Mitigation Strategies. Environments. 2023 Apr;10(4):66. https://doi.org/10.3390/environments10040066
- He Y, Liu WJ, Jia N, Richardson S, Huang C. Viral respiratory infections in a rapidly changing climate: the need to prepare for the next pandemic. eBioMedicine. 2023 May 9;93:104593. https://doi.org/10.1016/j.ebiom.2023.104593
- Sabin NS, Calliope AS, Simpson SV, Arima H, Ito H, Nishimura T, et al. Implications of human activities for (re)emerging infectious diseases, including COVID-19. J Physiol Anthropol. 2020 Sep 25;39:29. https://doi.org/10.1186/s40101-020-00233-6
- Alcayna T, Fletcher I, Gibb R, Tremblay L, Funk S, Rao B, et al. Climate-sensitive disease outbreaks in the aftermath of extreme climatic events: A scoping review. One Earth. 2022 Apr 15;5(4):336–50. https://doi.org/10.1016/j.oneear.2022.03.007
- Issa R, Sarsour A, Cullip T, Toma S, Ruyssen I, Scheerens C. Gaps and opportunities in the climate change, migration and health nexus: Insights from a questionnaire based study. J Migr Health. 2023 Mar 23;7:100171. https://doi.org/10.1016/j.jmh.2023.100171
- Liao H, Lyon CJ, Ying B, Hu T. Climate change, its impact on emerging infectious diseases and new technologies to combat the challenge. Emerg Microbes Infect. 2024;13(1):2356143. https://doi.org/10.1080/22221751.2023.2356143
- Piscitelli P, Miani A. Climate Change and Infectious Diseases: Navigating the Intersection through Innovation and Interdisciplinary Approaches. Int J Environ Res Public Health. 2024 Mar;21(3):314. https://doi.org/10.3390/ijerph21030314
- Adepoju OA, Afinowi OA, Tauheed AM, Danazumi AU, Dibba LBS, Balogun JB, et al. Multisectoral Perspectives on Global Warming and Vector-borne Diseases: a Focus on Southern Europe. Curr Trop Med Rep. 2023;10(2):47–70. https://doi.org/10.1007/s40475-023-00260-9
- Caminade C, McIntyre KM, Jones AE. Impact of recent and future climate change on vector‐borne diseases. Ann N Y Acad Sci. 2019 Jan;1436(1):157–73. https://doi.org/10.1111/nyas.13950
- Acosta-España JD, Romero-Alvarez D, Luna C, Rodriguez-Morales AJ. Infectious disease outbreaks in the wake of natural flood disasters: global patterns and local implications. Infez Med. 2024;32(4):451–62.
- Zhao AP, Li S, Cao Z, Hu PJH, Wang J, Xiang Y, et al. AI for science: Predicting infectious diseases. J Saf Sci Resilience. 2024 Jun 1;5(2):130–46. https://doi.org/10.1016/j.jssr.2024.05.004
- Wegner GI, Murray KA, Springmann M, Muller A, Sokolow SH, Saylors K, et al. Averting wildlife-borne infectious disease epidemics requires a focus on socio-ecological drivers and a redesign of the global food system. eClinicalMedicine. 2022 Apr 18;47:101386. https://doi.org/10.1016/j.eclinm.2022.101386
- Agusi ER, Allendorf V, Eze EA, Asala O, Shittu I, Dietze K, et al. SARS-CoV-2 at the Human–Animal Interface: Implication for Global Public Health from an African Perspective. Viruses. 2022 Nov 9;14(11):2473. https://doi.org/10.3390/v14112473
- Yarzábal LA, Salazar LMB, Batista-García RA. Climate change, melting cryosphere and frozen pathogens: Should we worry…? Environ Sustain (Singap). 2021;4(3):489–501. https://doi.org/10.1007/s42398-021-00197-w
- Imberti L, Tiecco G, Logiudice J, Castelli F, Quiros‐Roldan E. Effects of Climate Change on the Immune System: A Narrative Review. Health Sci Rep. 2025 Apr 18;8(4):e70627. https://doi.org/10.1002/hsr2.7062
- Pfenning-Butterworth A, Buckley LB, Drake JM, Farner JE, Farrell MJ, Gehman ALM, et al. Interconnecting global threats: climate change, biodiversity loss, and infectious diseases. Lancet Planet Health. 2024 Apr;8(4):e270. https://doi.org/10.1016/S2542-5196(24)00049-5
- Mojahed N, Mohammadkhani MA, Mohamadkhani A. Climate Crises and Developing Vector-Borne Diseases: A Narrative Review. Iran J Public Health. 2022 Dec;51(12):2664–73.
- Masse RS, Vythilingam I, Fornace K, Othman H, Liu X, Jaafar AJ, et al. Impact of environmental factors on the bionomics of Anopheles mosquito vectors of zoonotic malaria: A narrative review. One Health. 2025 Jul 14;101141. https://doi.org/10.1016/j.onehlt.2024.101141
- Lühken R, Brattig N, Becker N. Introduction of invasive mosquito species into Europe and prospects for arbovirus transmission and vector control in an era of globalization. Infect Dis Poverty. 2023 Nov 30;12(1):109. https://doi.org/10.1186/s40249-023-01128-7
- Delrieu M, Martinet JP, O’Connor O, Viennet E, Menkes C, Burtet-Sarramegna V, et al. Temperature and transmission of chikungunya, dengue, and Zika viruses: A systematic review. Curr Res Parasitol Vector Borne Dis. 2023 Aug 24;4:100139. https://doi.org/10.1016/j.crpvbd.2023.100139
- Couper LI, MacDonald AJ, Mordecai EA. Impact of prior and projected climate change on US Lyme disease incidence. Glob Chang Biol. 2021 Feb;27(4):738–54. https://doi.org/10.1111/gcb.15432
- Usmani M, Brumfield KD, Jamal Y, Huq A, Colwell RR, Jutla A. A Review of the Environmental Trigger and Transmission Components for Prediction of Cholera. Trop Med Infect Dis. 2021 Aug 5;6(3):147. https://doi.org/10.3390/tropicalmed6030147
- Kaljee LM, Pach A, Garrett D, Bajracharya D, Karki K, Khan I. Social and Economic Burden Associated With Typhoid Fever in Kathmandu and Surrounding Areas: A Qualitative Study. J Infect Dis. 2018 Nov 10;218(suppl_4):S243–9. https://doi.org/10.1093/infdis/jiy479
- Folorunsho S. The Role of Social Determinants of Health in Shaping Racial and Disability Disparities Among Older Adults in the United States. J Aging Soc Policy. 2025;1–17. https://doi.org/10.1080/08959420.2025.2329841
- Bradley EA, Lockaby G. Leptospirosis and the Environment: A Review and Future Directions. Pathogens. 2023 Sep 16;12(9):1167. https://doi.org/10.3390/pathogens12091167
- Folorunsho S, Ajayi V, Sanmori M, Suleiman M, Abdullateef R, Abdulganiyu A. Access to and Utilization of Dental Care Services by Older Adults in Nigeria: Barriers and Facilitators. Spec Care Dentist. 2025;45(3):e70040. https://doi.org/10.1111/scd.70040
- Hauser N, Gushiken AC, Narayanan S, Kottilil S, Chua JV. Evolution of Nipah Virus Infection: Past, Present, and Future Considerations. Trop Med Infect Dis. 2021 Feb 14;6(1):24. https://doi.org/10.3390/tropicalmed6010024
- Poirier O, Castañeda RR de, Bolon I, Ray N. Modelling forest degradation and risk of disease outbreaks in mainland Equatorial Guinea. J Public Health Emerg. 2021 Jun 25;5(0). Available from: https://jphe.amegroups.org/article/view/7288
- Elechi KW, Igboaka CD, Tiamiyu BB, Ugbor MJE, Arthur C, Ezeh OM, et al. Phytochemical Screening of Ficus globosa Latex (Moraceae) as a Source of Novel Antimicrobial Compounds. Path Sci. 2025 Mar 31;11(3):9001–10. https://doi.org/10.22178/pos.1103-2
- Hemmeda L, Shabani MM, Kolawole BO, Muhammad SA, Fatima K, Siddiqui A, et al. Third wave of COVID-19 pandemic in Africa: Challenges and recommendations. Ann Med Surg. 2022 Aug;80. Available from: https://journals.lww.com/annals-of-medicine-and-surgery/fulltext/2022/08000/third_wave_of_covid_19_pandemic_in_africa_.189.aspx
- Carlson CJ, Albery GF, Merow C, Trisos CH, Zipfel CM, Eskew EA, et al. Climate change increases cross-species viral transmission risk. Nature. 2022 Jul;607(7919):555–62. https://doi.org/10.1038/s41586-022-04788-w
- Lawal OP, Igwe EP, Olosunde A, Chisom EP, Okeh DU, Olowookere AK, et al. Integrating Real-Time Data and Machine Learning in Predicting Infectious Disease Outbreaks. Asian J Microbiol Biotechnol. 2025 May;10(1):147–63. https://doi.org/10.9734/ajmob/2025/v10i1203
- Folorunsho S, Ajayi V, Abdulrazaq O. Juvenile delinquency as a contemporary issue in Nigeria. Afr J Soc Issues. 2024 Mar 23;7(1):116–32. https://doi.org/10.5281/zenodo.10920064
- McMichael AJ, Woodruff RE. Climate change and infectious diseases. In: Mayer KH, Pizer HF, editors. The Social Ecology of Infectious Diseases. San Diego: Academic Press; 2008. p. 378–407. Available from: https://www.sciencedirect.com/science/article/pii/B9780123704665500194
- D’Amore C, Grimaldi P, Ascione T, Conti V, Sellitto C, Franci G, et al. West Nile Virus diffusion in temperate regions and climate change. Infez Med. 2023 Mar 1;31(1):20–30.
- Adepoju OA, Afinowi OA, Tauheed AM, Danazumi AU, Dibba LBS, Balogun JB, et al. Multisectoral Perspectives on Global Warming and Vector-borne Diseases. Curr Trop Med Rep. 2023;10(2):47–70. https://doi.org/10.1007/s40475-023-00260-9
- Ezhova E, Orlov D, Suhonen E, Kaverin D, Mahura A, Gennadinik V, et al. Climatic Factors Influencing the Anthrax Outbreak of 2016 in Siberia, Russia. Ecohealth. 2021;18(2):217–28. https://doi.org/10.1007/s10393-021-01531-4
- Aik J, Ong J, Ng LC. The effects of climate variability and seasonal influence on diarrhoeal disease in Singapore. Int J Hyg Environ Health. 2020 Jun 1;227:113517. https://doi.org/10.1016/j.ijheh.2020.113517
- Ryan SJ, Lippi CA, Zermoglio F. Shifting transmission risk for malaria in Africa with climate change. Malar J. 2020 May 1;19:170. https://doi.org/10.1186/s12936-020-03259-1
- Ndishimye P, Umuhoza T, Umutoni B, Zakham F, Ndayambaje M, Hewins B, et al. Rift Valley Fever outbreaks in the East African Community. Front Public Health. 2024 Dec 11;12:1298594. https://doi.org/10.3389/fpubh.2024.1298594
- Hassell JM, Begon M, Ward MJ, Fèvre EM. Urbanization and Disease Emergence: Dynamics at the Wildlife–Livestock–Human Interface. Trends Ecol Evol. 2017 Jan;32(1):55–67. https://doi.org/10.1016/j.tree.2016.09.012
- Jamal MK, Sanaei B, Naderi M, Past V, Abadi SHA, Khazaei R, et al. Investigating the recent outbreak of dengue fever in Iran. Egypt J Intern Med. 2025 Feb 18;37(1):37. https://doi.org/10.1186/s43162-025-00224-9
- Sah R, Mohanty A, Rohilla R, Asija A, Sedhai YR, Chandran D, et al. Japanese encephalitis prevalence and outbreaks in Nepal. Int J Surg. 2023 Mar 3;110(10):6822. https://doi.org/10.1016/j.ijsu.2023.106822
- Beermann S, Dobler G, Faber M, Frank C, Habedank B, Hagedorn P, et al. Impact of climate change on vector- and rodent-borne infectious diseases. J Health Monit. 2023 Jun 1;8(Suppl 3):33.
- Wang HR, Liu T, Gao X, Wang HB, Xiao JH. Impact of climate change on West Nile virus and adaptation responses. Infect Dis Poverty. 2024 May 24;13(1):38. https://doi.org/10.1186/s40249-024-01174-5
- Douglas KO, Payne K, Sabino-Santos G, Agard J. Influence of Climatic Factors on Human Hantavirus Infections in Latin America and the Caribbean. Pathogens. 2021 Dec 23;11(1):15. https://doi.org/10.3390/pathogens11010015
- El-Sayed A, Kamel M. Climatic changes and their role in emergence and re-emergence of diseases. Environ Sci Pollut Res Int. 2020;27(18):22336–52. https://doi.org/10.1007/s11356-020-08764-6
- Kraemer MUG, Reiner RC Jr, Brady OJ, Messina JP, Gilbert M, Pigott DM, et al. Past and future spread of Aedes aegypti and Aedes albopictus. Nat Microbiol. 2019 Mar 4;4(5):854. https://doi.org/10.1038/s41564-019-0376-y
- Muluneh MG. Impact of climate change on biodiversity and food security: A review. Agric Food Secur. 2021 Sep 6;10(1):36. https://doi.org/10.1186/s40066-021-00325-y
- Liao H, Lyon CJ, Ying B, Hu T. Climate change, its impact on emerging infectious diseases and new technologies to combat the challenge. Emerg Microbes Infect. 2024;13(1):2356143. https://doi.org/10.1080/22221751.2023.2356143
- Martins FP, Paschoalotto MAC, Closs J, Bukowski M, Veras MM. The Double Burden: Climate Change Challenges for Health Systems. Environ Health Insights. 2024 Nov 20;18:11786302241298789. https://doi.org/10.1177/11786302241298789
- Lawal O, Oyebamiji HO, Kelenna IJ, Chioma FJ, Oyefeso E, Adeyemi BI, et al. A Review on Usage of Digital Health Literacy to Combat Antibiotic Misuse in Nigeria. J Pharma Insights Res. 2025 Apr 5;3(2):258–69.
- Onwuemelem LA, Orobator ET, Onyedum NN, Chibueze ES, Kanu I, Christopher AA, et al. Molecular Mechanisms of Clonal Hematopoiesis in Age-Related Cardiovascular Disease. J Pharma Insights Res. 2025 Apr 5;3(2):358–72.
- Hess JJ, McDowell JZ, Luber G. Integrating Climate Change Adaptation into Public Health Practice. Environ Health Perspect. 2011 Oct 13;120(2):171. https://doi.org/10.1289/ehp.1103515
- Thiede BC, Strube J. Climate Variability and Child Nutrition: Findings from Sub-Saharan Africa. Glob Environ Change. 2020 Nov;65:102192. https://doi.org/10.1016/j.gloenvcha.2020.102192
- Lawal OP, Egwuatu EC, Akanbi KO, Orobator ET, Eweje OZ, Omotayo EO, et al. Fighting Resistance With Data: Leveraging Digital Surveillance in Nigeria. Path Sci. 2025 Mar 31;11(3):1009–17. https://doi.org/10.22178/pos.1103-3
- Ayomide IT, Promise LO, Christopher AA, Okikiola PP, Esther AD, Favour AC, et al. The Impact of Antimicrobial Resistance on Co-INFECTIONS. Int J Pathogen Res. 2024 Nov 29;13(6):117–28.
- Pronyk PM, Alwis R de, Rockett R, Basile K, Boucher YF, Pang V, et al. Advancing pathogen genomics in resource-limited settings. Cell Genomics. 2023 Nov 17;3(12):100443. https://doi.org/10.1016/j.xgen.2023.100443
- Hobusch U, Scheuch M, Heuckmann B, Hodžić A, Hobusch GM, Rammel C, et al. One Health Education Nexus. Front Public Health. 2024 Mar 22;11:1337748. https://doi.org/10.3389/fpubh.2023.1337748
- Lawal O, Elechi K, Adekunle F, Farinde O, Kolapo T, Igbokwe C, et al. A Review on Artificial Intelligence and Point-of-Care Diagnostics in Nigeria. J Pharma Insights Res. 2025 Apr 5;3(2):166–75.
- Oseghale ID, Lawal OP, Ubebe DO, Orjiewulu VC, Igunma AA, Odey OP, et al. Ethnomedicinal and Phytopharmacological Aspects of Vernonia amygdalina. Asian J Res Biochem. 2024 Oct 14;14(6):41–57. https://doi.org/10.9734/ajrb/2024/v14i62403
LICENSE

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.