EPIDEMIOLOGY AND HEALTH DATA INSIGHTS
Original Article
Aug 06, 2026 4 2

Clinical Characteristics and Comorbidities of Pediatric Atopic Dermatitis in an Algerian Cohort: Relevance to Contemporary Therapeutic Management

Auda Ameur 1 2 * ,
Wiam Saadi 3,
Charef Latroch 2,
Ahlam Fatmi 4,
Karim Bouziane Nedjadi 2,
Véronique Desvignes 5 6
1 Pediatric Dermatologist, University of Oran 1, Oran, Algeria2 Department of Pediatrics B, Amilcar Cabral, Oran University Hospital, Oran, Algeria3 Department of Biology, Faculty of Nature, Life and Earth Sciences, University of Djillali Bounaama, Khemis Miliana, Algeria4 Department of Microbiology & Biochemistry, Faculty of Science, University of M’sila, M’sila, Algeria5 Department of Pediatrics, Clermont-Ferrand University Hospital, Clermont-Ferrand, France6 Scientific Committee, French Association of Ambulatory Pediatrics (AFPA), Saint-Géréon, France* Corresponding Author
Epidemiology and Health Data Insights, 2(5), 2026, ehdi051, https://doi.org/10.63946/ehdi/19085
Publication date: Aug 06, 2026
Full Text (PDF)

ABSTRACT

Background: Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease characterized by intense pruritus, xerosis, recurrent eczematous lesions, and impaired quality of life. Although AD is common in North Africa, data on its associated comorbidities in Algerian children remain scarce.
Objective: To characterize the clinical profile and associated comorbidities of pediatric atopic dermatitis in an Algerian cohort and to review current therapeutic advances.
Methods: We conducted a retrospective cross-sectional study including 53 children diagnosed with atopic dermatitis according to the Hanifin and Rajka criteria at the Pediatric Dermatology Unit of the University Hospital of Oran, Algeria, between January 2025 and January 2026. Demographic characteristics, clinical manifestations, allergic comorbidities, family history, and quality of life assessed using the Children's Dermatology Life Quality Index (CDLQI) were analyzed.
Results: Atopic dermatitis represented 4.42% of all dermatology consultations during the study period. The mean age was 6.7 years, with a female predominance. Familial atopy was the most frequent comorbidity (90.6%), followed by familial asthma (49.1%) and familial eczema (43.4%). Among personal allergic comorbidities, asthma affected 26.4%, allergic rhinitis 24.5%, and allergic conjunctivitis 11.3% of patients. Personal atopy was significantly associated with asthma (OR = 7.9, 95% CI: 2.46–25.46), food allergy (OR = 6.2, 95% CI: 2.30–17.10), allergic conjunctivitis (OR = 4.1, 95% CI: 1.50–11.29), and allergic rhinitis (OR = 3.5, 95% CI: 1.38–9.22). Quality of life was markedly affected, with sleep disturbances reported in 92.5% of patients, stress and anxiety in 50.9%, reduced daily activities in 34.0%, and school absenteeism in 32.1%.
Conclusion: Pediatric atopic dermatitis in this Algerian cohort was characterized by a high burden of allergic comorbidities, a strong familial atopic background, and a substantial impact on quality of life. Early recognition of associated conditions and timely multidisciplinary management are essential to improve patient outcomes and may help reduce progression along the atopic march.

KEYWORDS

Algeria Atopic Dermatitis Skin Immunology Type 2 Inflammation

CITATION (Vancouver)

Ameur A, Saadi W, Latroch C, Fatmi A, Bouziane Nedjadi K, Desvignes V. Clinical Characteristics and Comorbidities of Pediatric Atopic Dermatitis in an Algerian Cohort: Relevance to Contemporary Therapeutic Management. Epidemiology and Health Data Insights. 2026;2(5):ehdi051. https://doi.org/10.63946/ehdi/19085
APA
Ameur, A., Saadi, W., Latroch, C., Fatmi, A., Bouziane Nedjadi, K., & Desvignes, V. (2026). Clinical Characteristics and Comorbidities of Pediatric Atopic Dermatitis in an Algerian Cohort: Relevance to Contemporary Therapeutic Management. Epidemiology and Health Data Insights, 2(5), ehdi051. https://doi.org/10.63946/ehdi/19085
Harvard
Ameur, A., Saadi, W., Latroch, C., Fatmi, A., Bouziane Nedjadi, K., and Desvignes, V. (2026). Clinical Characteristics and Comorbidities of Pediatric Atopic Dermatitis in an Algerian Cohort: Relevance to Contemporary Therapeutic Management. Epidemiology and Health Data Insights, 2(5), ehdi051. https://doi.org/10.63946/ehdi/19085
AMA
Ameur A, Saadi W, Latroch C, Fatmi A, Bouziane Nedjadi K, Desvignes V. Clinical Characteristics and Comorbidities of Pediatric Atopic Dermatitis in an Algerian Cohort: Relevance to Contemporary Therapeutic Management. Epidemiology and Health Data Insights. 2026;2(5), ehdi051. https://doi.org/10.63946/ehdi/19085
Chicago
Ameur, Auda, Wiam Saadi, Charef Latroch, Ahlam Fatmi, Karim Bouziane Nedjadi, and Véronique Desvignes. "Clinical Characteristics and Comorbidities of Pediatric Atopic Dermatitis in an Algerian Cohort: Relevance to Contemporary Therapeutic Management". Epidemiology and Health Data Insights 2026 2 no. 5 (2026): ehdi051. https://doi.org/10.63946/ehdi/19085
MLA
Ameur, Auda et al. "Clinical Characteristics and Comorbidities of Pediatric Atopic Dermatitis in an Algerian Cohort: Relevance to Contemporary Therapeutic Management". Epidemiology and Health Data Insights, vol. 2, no. 5, 2026, ehdi051. https://doi.org/10.63946/ehdi/19085

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